Anti-cancer Medication Use During Pregnancy – Neonatal Outcomes – HMC Continuing Pharmacy Professional Development

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Session Title :Anti-cancer Medication Use During Pregnancy – Neonatal Outcomes

Presenter :Heba Al Taweel , clinical pharmacist , WWRC

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PharmacistClinical PharmacistPharmacy Technicain Other

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Question 1 of 6

1. Question
The use of chemotherapy during the second trimester is considered unsafe and is associated with the highest risk of neonatal malformations
- True
- False
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Question 2 of 6

2. Question
The following are neonatal adverse effects commonly linked with cytotoxic agents excepts:
- Oligohydramnios
- Intra-uterine growth restriction
- Pre-term delivery
- Increased renal impairment
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Question 3 of 6

3. Question
Tamoxifen is contraindicated during pregnancy because it has been linked to cause Goldenhar syndrome and ambiguous genitalia.
- True
- False
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Question 4 of 6

4. Question
From the case studies discussed, mothers receiving chemotherapy during pregnancy found all of the following neonatal outcomes except:
- Normal fetal growth
- Respiratory distress syndrome
- Anemia
- Facial malformations
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Question 5 of 6

5. Question
The most common type of cancer during pregnancy is:
- Cervical
- Ovarian
- Breast
- Malignant lymphoma
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Question 6 of 6

6. Question
A patient is receiving a chemotherapy agent which has a high plasma protein binding. The physician asks you as the pharmacist, does this mean that there is a higher risk of transfer through the placenta?
- Yes, there is a higher risk that the medication will cross the placenta since it has high protein binding
- No, the risk of it crossing the placenta is reduced due to its high lipid soluble characteristic
- Not sure, ask the oncologist
- No, the risk of it crossing the placenta is reduced since medications with low protein binding are the ones with higher placental transfer. However, risk cannot be 100% disregarded.
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Presenter :Heba Al Taweel , clinical pharmacist , WWRC

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