Patent Ductus Arteriosis (PDA) in Neonates

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Session Title :Patent Ductus Arteriosis (PDA) in Neonates

Presenter :Heba Mohamed Al-Taweel , Clinical pharmacist, WWRC

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Question 1 of 6

1. Question
PDA is the process in which the ductus arteriosus (which connects the aortic arch and pulmonary artery) is closed
- True
- False
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Question 2 of 6

2. Question
Which of the following clinical manifestations may occur when a neonate is presenting with PDA except
- Asymptomatic
- Murmur (diastolic)
- Murmur (systolic/systolic-diastolic) and bounding pulses
- Difficulty with feeding
Correct

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Question 3 of 6

3. Question
The scoring system used for assessment of severity of symptoms is known as Cardiovascular Disease Score (CVD)?
- True
- False
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Question 4 of 6

4. Question
What is appropriate short-term (3 day) dosing regimen for Ibuprofen in PDA?
- 20mg/kg (initial dose)  10mg/kg at 24 and 48 hours
- 8mg/kg (initial dose)  4mg/kg at 24 and 48 hours
- 10mg/kg (initial dose)  5mg/kg at 24 and 48 hours
- 15mg/kg (initial dose)  10mg/kg at 24 and 48 hours
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Question 5 of 6

5. Question
Baby BR is found to have PDA, and the physician decides to treat the neonate with indomethacin. The neonates post-natal age is 5 days. The physician recalls that the initial dose for indomethacin is 0.2mg/kg/dose, however contacts you for assistance on what the appropriate dose is at 12 and 24 hours. What is the response you give him?
- The dose is the same for the remaining 2 dosing intervals
- Initiate the baby on 0.1mg/kg
- Initiate the baby on 0.2mg/kg
- Initiate the baby on 0.2mg/kg at 12 hours followed by 0.25mg/kg at 24 hours
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Question 6 of 6

6. Question
A resident approaches you and explains he would like to initiate the baby on Paracetamol as he as read a study on its efficacy and safety compared to current therapies. Which is the best answer to his inquiry?
- Paracetamol should be started at a dose of 7.5mg/kg
- Yes, initiate therapy however because it is new I would recommend to start it alongside ibuprofen or indomethacin as they are mainstay therapy
- Paracetamol is a promising therapy however, its use has still not been approved/implemented in all centers.
- Recommend that he reads more studies prior to starting therapy as reading one study is not enough to formulate an opinion
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Presenter :Heba Mohamed Al-Taweel , Clinical pharmacist, WWRC